Description
The U.S. Food and Drug Administration (FDA) is seeking a Field-Flow Fractionation Multi-Angle Light Scattering (FFF-MALS) System with Size Exclusion Chromatography Multi-Angle Light Scattering/Refractive Index (SEC/MALS/RI) and variable wavelength Ultraviolet detection capability. The system must meet specific requirements, including the ability to perform Size Exclusion Chromatography and characterize molecules through the determination of molecular mass, hydrodynamic radius, polydispersity, and concentration. The system will be used to analyze proteins, peptides, vaccines, and polymers.
Some key features of the system include:
• Supports flow rate of at least 5 mL/min
• Allows regulation of cross flow in a range of at least 0.03-5 mL/min
• Instrument and channels must be compatible with both aqueous and organic solvents
• Ability to regulate temperature of FFF channels
• Detector flow rate control with a precision of 0.1% or better
The contract will be a firm fixed-price contract, and the award will be made using simplified acquisition procedures. The evaluation factors will include the ability to fulfill the minimum requirements of the government and price.