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U.S. National Institutes of Health·United States of America

NIH Director?s Pioneer Award (DP1 Clinical Trial Optional)

Closes 9/9/2026$700k – $3.5MGrants Notice
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Description

The NIH Director's Pioneer Award supports individual scientists of exceptional creativity who propose bold and highly innovative research projects with the potential to produce a major impact on broad, important areas relevant to the mission of NIH. To be considered pioneering, the proposed research must reflect substantially different scientific directions from those already being pursued in the investigator's research program or elsewhere. Applications in all topics relevant to the broad mission of NIH are welcome. Research may involve basic, translational, or clinical research. The award is a component of the High-Risk, High-Reward Research (HRHR) program of the NIH Common Fund. Key aspects of this opportunity include: * The award is for individual scientists, not teams or institutions. * The research project must be highly innovative and have the potential to produce a major impact on the mission of NIH. * Applications in all topics relevant to the broad mission of NIH are welcome. * The award is for a period of 5 years, with a maximum budget of $700,000 per year. * The award is a component of the HRHR program, which aims to support high-risk, high-reward research.

Attached files

Contact

Nawall Kertache

[email protected]

(877) 464-4772

Key dates

Opened
12/11/2025
Closes
9/9/2026
Projected award
9/15/2026
Duration
5 years

Last updated

Details

Type
Grants Notice
Industry
Healthcare and Medical Services
NAICS
541710
Solicitation №
RFA-RM-27-001

Budget estimate

$700,000 – $3,500,000

The estimated budget for this opportunity is between $700,000 and $3,500,000 over 5 years, based on the maximum budget of $700,000 per year. The actual budget may vary depending on the specific research project and the number of awards made. The factors that may influence the likely payment range include the scope and complexity of the research project, the qualifications and experience of the investigator, and the availability of funds.

AI estimate from the solicitation

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