Translational Research in Maternal and Pediatric Pharmacology and Therapeutics (R01 Clinical Trial Optional)

The purpose of this notice of funding opportunity (NOFO) is to support translational and clinical research to advance precision medicine in pregnant women, lactating women, and children through the development of novel tools, models, and other technologies that could have a direct clinical or health impact. The overall goal is to improve safe and effective precision therapeutics for pregnant and lactating women, fetuses, neonates, and children, including those with disabilities. Key aspects of the opportunity include: • Advancing precision medicine in pregnant women, lactating women, and children • Developing novel tools, models, and technologies for direct clinical or health impact • Enhancing understanding of the underlying mechanisms of drug action • Discovering and developing novel therapeutics or enhancing the usage of existing drugs • Improving safe and effective precision therapeutics for the target populations