Description
The purpose of this NOFO is to announce support for meritorious research projects that address research questions relevant to human dental, oral, or craniofacial (DOC) biology, and diseases and conditions, through analysis of existing and publicly available genomic data. Data analysis for each project can be performed using existing and/or novel methods, including methods for data and metadata mining, data integration, and Artificial Intelligence (AI)/Machine Learning (ML)/Deep Learning (DL) methods. In addition to analysis of existing data, experimental or in silico work is required to validate the results of the proposed analysis, or to validate a newly developed analytic method. Key aspects of this opportunity include:
• Analysis of existing genomic data to address research questions relevant to human dental, oral, or craniofacial biology and diseases
• Use of statistical and computational approaches, including AI/ML/DL methods
• Requirement for experimental or in silico work to validate results or newly developed analytic methods
• Priority given to projects aimed at understanding oral health disparities and informing strategies for improving health for all individuals
• Encouragement of projects focused on investigating and/or characterizing human biological pathways to inform identification of intervention targets or defining the pathogenicity of known genetic variants