AJ11--Synthesis of Cyclic Peptide NPC86

The James A. Haley VA Medical Center is seeking a sole source provider for the synthesis of a cyclic peptide called NPC86. The peptide is designed to alleviate metabolic diseases such as type 2 diabetes and neurodegenerative diseases. The target is to synthesize 2 grams of NPC86 with a purity of 95% by HPLC. The synthesis method will be Solid Phase Peptide Synthesis (SPPS) on Rink amide resin. The period of performance is from August 17, 2026, to August 16, 2027. • The contract is for a highly specialized synthesis of a new drug. • The target specification for the final compound is 95% purity by HPLC. • The synthesis method will be Solid Phase Peptide Synthesis (SPPS) on Rink amide resin. • The period of performance is from August 17, 2026, to August 16, 2027.