The National Institutes of Health (NIH) is seeking a quotation for the lease and potential purchase of an Iconeus-One Xcel System, a functional ultrasound system that allows for whole brain imaging in awake, freely moving rodents in various behavioral conditions. The system must have specific features such as ultra-high sensitivity doppler imaging, unparalleled spatiotemporal functional resolution, and real-time neurofunctional monitoring. The system will be used for research on substance use disorder, addiction, and relapse.
• The Iconeus-One Xcel System must have a portable imaging station with a four-axis motorized scanning platform and interactive live imaging with a reference atlas.
• The system must allow for simultaneous acquisition of large amounts of data and efficient removal of non-vascular signals from surrounding tissues.
• The system must have a software suite that maps intrinsic brain connectivity, task-based functional neuroimaging, and vasculature imaging analysis.
• The system must be compatible with the Phenosys JetBall and Neurotar Mobile Home Cage.
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