Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Assay Development and Therapeutic Agent Identification

The National Institute of Neurological Disorders and Stroke, National Institute of Aging, and other participating NIH Institutes/Centers seek to support applications to develop in vitro, ex vivo, or in vivo assays and conduct screening efforts with the goal of identifying and characterizing potential therapeutic agents for disorders or diseases supported by participating ICs, or for non-opioid analgesic therapeutics with little or no addiction liability as a part of the NIH Helping to End Addiction Long Term (HEAL) initiative. • The initiative aims to support the development of assays and screening efforts for potential therapeutic agents. • Therapeutic agents include small molecules and biologics. • Assays utilizing New Approach Methodologies (NAMs) may be used when appropriate. • The opportunity is forecasted, and applications are not being solicited at this time, but potential applicants are encouraged to develop meaningful collaborations and responsive projects.