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U.S. National Institutes of Health·United States of America

Health and Extreme Weather Solutions-Focused Research Hubs (U54 - Clinical Trial Optional)

Closes 1/28/2027$1M – $3MGrants Notice
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Description

The National Institute of Environmental Health Sciences (NIEHS) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for translational research hubs focused on the health impacts of extreme weather and cumulative exposures. The hubs will conduct research, capacity building, and community/public health translation, and will be led by a multidisciplinary team of investigators with non-academic partners. The research can be situated at different nodes on the translational research continuum, spanning from fundamental to implementation research, and should clearly inform pathways to support implementation, scalability, and measurable public health impact. • The hubs will focus on regionally relevant topics related to the health impacts of extreme weather and cumulative exposures. • The hubs will be led by a multidisciplinary team of investigators with non-academic partners. • The research will be situated at different nodes on the translational research continuum. • The hubs will be expected to collaborate with the HEW Research Coordination and Data Center(s) and other members of the HEW Community of Practice. • The NOFO will utilize the U54 activity code, which supports specialized centers that function as regional resources for targeted research initiatives.

Attached files

The solicitation documents live at the source — open the bid source above to download them.

Contact

[email protected]

Key dates

Opened
6/26/2026
Closes
1/28/2027
Projected award
12/1/2027

Last updated

Details

Type
Grants Notice
Industry
Healthcare and Medical Services
NAICS
541710
Solicitation №
RFA-ES-28-002

Budget estimate

$1,000,000 – $3,000,000

The estimated funding for this opportunity is $18,000,000, with an award ceiling of $2,000,000. The budget estimation is based on the estimated funding and the number of awards, which is expected to be 6. The budget range is estimated to be between $1,000,000 and $3,000,000, depending on the specific project and the number of awards. The factors that may influence the likely payment range include the scope of the project, the number of partners involved, and the level of federal programmatic staff involvement.

AI estimate from the solicitation

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