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U.S. National Institutes of Health·United States of America

Bioengineering Research Grants (BRG) (R01 Clinical Trial Optional)

Closes 7/5/2029$100k – $500kGrants Notice
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Description

The National Institutes of Health (NIH) is seeking multidisciplinary bioengineering research projects that integrate life‑ and physical‑science approaches to solve biomedical problems, with an optional R01‑style clinical trial component. Applications may be design‑directed, developmental, discovery‑driven, or hypothesis‑driven and are intended for small teams. The program will fund up to 50 awards, each with a ceiling of $500,000, and does not support conventional Phase III clinical trials or commercial production. Eligible applicants include a wide range of public, private, nonprofit, and for‑profit entities, including foreign organizations. • Focus: Multidisciplinary bioengineering solutions for basic, translational, or clinical science. • Funding mechanism: NIH Grant (R01 Clinical Trial Optional). • Award ceiling: $500,000 per award; up to 50 awards. • Project period: Up to 5 years (typical R01 duration). • Eligibility: U.S. state, local, tribal, and private institutions; foreign organizations allowed under NIH policy. • Submission window: Opens Sep 5 2026, closes Jul 5 2029. • Award date: Expected Dec 1 2026; project start same date. • Required deliverables: Data Management & Sharing Plan, annual RPPRs, final close‑out reporting. • No pre‑bid meeting or mandatory site visit. • Primary contact: Bioengineering Research Grants, NCI (email above).

Attached files

Contact

Miguel R. Ossandon, Ph.D.(Scientific/Research Contact)

[email protected]

(301) 402-2541

Key dates

Opened
9/9/2025
Closes
7/5/2029
Projected award
12/1/2026
Duration
5 years

Last updated

Details

Type
Grants Notice
Industry
Engineering Services
NAICS
541715
Solicitation №
PAR-27-072

Budget estimate

$100,000 – $500,000

The NOFO caps each award at $500,000 and anticipates up to 50 awards, indicating a total funding envelope of roughly $25 million. For an individual applicant, the expected award range is between $100,000 (typical for smaller, early‑stage projects) and the maximum $500,000. The exact amount will depend on project scope, team size, and the extent of the optional clinical‑trial component.

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