Medicinal Chemistry Support Program for Therapeutic Development

The National Institutes of Health (NIH) intends to modify an existing contract for medicinal chemistry support services to increase the contract's maximum value. The contract provides services including project management, compound logistics, synthesis, computational chemistry, and in vitro ADME studies in support of preclinical drug discovery efforts. The contractor must be able to continue work on existing projects and scale up or down staff as needed. The contract includes two performance areas: technical transfer, storage, handling, and distribution, as well as medicinal chemistry support. The goal of the contract is to advance preclinical candidate compounds for further development and ultimately bring new drugs to market. * The contract has a 10-year ordering period from March 16, 2018, to March 15, 2028. * The contract's maximum value will increase by $30,145,159, from $39,500,000 to $69,645,159. * The contractor must have the capacity to perform a range of medicinal chemistry services, including synthesis, computational chemistry, and in vitro ADME studies. * The contract is classified under NAICS code 541715, with a small business size standard of 1,000 employees.