Medicinal Chemistry Support for Therapeutic Development: Synthesis of HERV-K Protease Inhibitors

The National Institutes of Health (NIH) is seeking proposals for medicinal chemistry support for therapeutic development, specifically the synthesis of HERV-K protease inhibitors. The contract will be awarded to the responsible offeror whose proposal represents the best value to the Government, considering factors such as technical capability, price, past performance, and delivery schedule. Offerors must provide sufficient information to demonstrate their capability to provide the required product or service, including unit and total price, shipping and handling costs, delivery timeframe, and product or service description. • The associated NAICS code is 541380. • The small business size standard is N/A. • The requirement is not a set-aside for small businesses. • The Government intends to award a Firm-Fixed-Price contract. • The acquisition is conducted under the authority of FAR 12.603, Streamlined Solicitation for Commercial Products or Commercial Services. • The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2026-01 March 13, 2026.