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U.S. National Institutes of Health·United States of America

NIH Director?s Transformative Research Award for Individual and Group Science (R01 Clinical Trial Optional)

Closes 9/3/2026$1M – $2MGrants Notice
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Description

The NIH Director's Transformative Research Award supports individual scientists or groups of scientists proposing bold, groundbreaking, exceptionally innovative, original, and/or unconventional research with the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies. Applications in any area within the biomedical sciences are welcome; topics may involve basic, translational, or clinical research. No preliminary data are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling potential to produce a major impact in a broad area of relevance to the NIH. The key aspects of this opportunity include: * Support for innovative and unconventional research * Applications in any area within the biomedical sciences * No preliminary data required * Compelling potential to produce a major impact in a broad area of relevance to the NIH * Part of the High-Risk, High-Reward Research (HRHR) program of the NIH Common Fund

Attached files

Contact

Nawall Kertache

[email protected]

(877) 464-4772

Key dates

Opened
1/6/2026
Closes
9/3/2026
Projected award
8/30/2027
Duration
4 years

Last updated

Details

Type
Grants Notice
Industry
Healthcare and Medical Services
NAICS
541710
Solicitation №
RFA-RM-27-003

Budget estimate

$1,000,000 – $2,000,000

The estimated budget for this opportunity can be based on the estimated funding of $8,000,000 and the number of awards, which is 7. Assuming each award will receive a similar amount, the estimated budget per award would be around $1,142,857. However, this is only an estimate, and the actual budget may vary depending on various factors, including the specific research proposals and the NIH's funding decisions.

AI estimate from the solicitation

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