The fiscal year 2026 Peer Reviewed Cancer Research Program (PRCRP) Impact Award supports mature research that will have a near-term impact on clinical cancer care in one of the congressionally directed FY26 PRCRP Topic Areas. Applicants must consider how the research project will lead to the advancement of knowledge in cancer research, patient care and/or treatment options in the Military Health System (MHS). The funding mechanism allows clinical trials and has a maximum period of performance of 3 years. The program announcement must be read in conjunction with the General Application Instructions.
• The program announcement includes distinctive features such as the requirement for preliminary data, strong potential for near-term impact, and the option for a single Principal Investigator (PI) or two partnering PIs.
• The funding details include an expected allotment of $45.0M to fund approximately 30 Impact Award applications, with a maximum award amount of $1.5M per award.
• The submission and review dates include a pre-application submission deadline, invitation to submit an application, application submission deadline, and peer review and programmatic review dates.
• The program description includes information on the PRCRP, the FY26 PRCRP Topic Areas, and the FY26 PRCRP Strategic Goals.
• The application contents and format include a two-step application process, with requirements for pre-application and full application submissions.
• The submission requirements include locations for application packages, instructions for submitting pre-applications and full applications, and application verification.
• The application review information includes processes for application compliance review, pre-application and full application selection/notification, and risk assessment.
• The federal award notices include information on what a successful applicant can expect if recommended for funding.
• The post-award requirements include policy requirements for funded research, reporting requirements, and restrictions related to Principal Investigator changes and institutional award transfers.
• The other information includes criteria for administrative actions, such as rejection, modification, withdrawal, and withhold, as well as information on other funding opportunities.
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