NOI - Acquisition of a Sonication Device for Amyloid Seeding Experiments

The National Heart, Lung, and Blood Institute (NHLBI) intends to award a sole source purchase order for the acquisition of a sonication device to support amyloid seeding experiments. The required system must provide highly controlled, reproducible sonication of small-volume biological samples to enable standardized preparation of pre-formed fibrils (PFFs). The device should have features such as controlled cavitation, sealed-tube processing, continuous sample rotation, and validated reproducibility for PFF generation. Some key points about this opportunity include: • The acquisition is for a commercial product and is conducted under the authority of FAR 13.106-1(b)(1)—Soliciting from a Single Source. • The intended source is Hologic Sales and Service, LLC, which is the exclusive distributor of Bioruptor devices in the United States. • Interested parties may submit a capability statement demonstrating their ability to meet all minimum technical requirements. • The device will be used to support ongoing laboratory studies and enable high-quality, reproducible experimental outcomes consistent with current scientific standards.