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U.S. National Institutes of Health·United States of America

Small Business Transition Grant for New Entrepreneurs (Parent R43/R44 Clinical Trial Optional)

Closes 1/4/2027$100k – $500kGrants Notice
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Description

The National Institutes of Health (NIH) intends to publish a Notice of Funding Opportunity (NOFO) to invite eligible United States small business concerns (SBCs) to submit Small Business Innovation Research (SBIR) Phase I, and Fast-Track (NIH only) grant applications for the Small Business Transition Grant. The grant will support early-career scientists as they transition into entrepreneurship, with a focus on entrepreneurial training, mentoring, and career development of the PD/PI. Key points to consider: • The NOFO will utilize the R43/R44 activity code. • United States small businesses that have the research capabilities and technological expertise to contribute to the R&D mission(s) of the NIH and CDC awarding components are encouraged to apply. • First-time Principal Investigators are eligible to apply, and key personnel must include a mentor with measurable effort committed to the project. • The grant will support research and development efforts at the SBC, as well as entrepreneurial training and career development.

Attached files

The solicitation documents live at the source — open the bid source above to download them.

Contact

[email protected]

(301) 827-8595

Key dates

Opened
5/27/2026
Closes
1/4/2027
Projected award
6/1/2027

Last updated

Details

Type
Grants Notice
Industry
Healthcare and Medical Services
NAICS
541710
Solicitation №
PAR-27-039

Budget estimate

$100,000 – $500,000

The budget amount for this grant is not specified in the document, but based on the information provided, it can be estimated that the grant will likely be in the range of $100,000 to $500,000. This estimate is based on the fact that the grant will support research and development efforts, as well as entrepreneurial training and career development, and that the NIH typically provides funding for small business innovation research grants in this range. Factors that may influence the likely payment range include the scope of the project, the number of personnel involved, and the duration of the grant.

AI estimate from the solicitation

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