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U.S. Department Of Defense·Maryland

Dengue Mathematical Model

Closes 12/17/2025$500k – $2MSole Source
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Description

The United States Army Medical Research Acquisition Activity (USAMRAA) is seeking a contractor to develop mathematical models for Dengue Virus (DENV) infection. The objective of the research project is to assist with a study of the potential impact of DENV infection on military readiness. The contractor will develop mathematical models that address the probability of infection given travel to specific places at specific times, the probability of apparent illness upon infection, and the duration and severity of that apparent illness. The contractor will also build a clinical pathway model that quantifies the probability of illness upon infection and integrate these models with the probability of apparent disease to provide a web-based tool that estimates the risk of illness for military personnel deployed to specific settings at specific times of year. • The contractor will develop mathematical models for DENV infection. • The contractor will build a clinical pathway model that quantifies the probability of illness upon infection. • The contractor will integrate these models with the probability of apparent disease to provide a web-based tool. • The contractor will provide a web-based tool that estimates the risk of illness for military personnel deployed to specific settings at specific times of year.

Attached files

Contact

Joshua Dean

[email protected]

(301) 619-2302

Key dates

Opened
12/11/2025
Closes
12/17/2025
Duration
24 months

Last updated

Details

Type
Sole Source
Industry
Healthcare and Medical Services
NAICS
541715
Solicitation №
FY25-0083

Budget estimate

$500,000 – $2,000,000

The estimated budget for this contract is not specified in the document, but based on the complexity of the project and the fact that it is a sole source contract, the budget could be substantial. The contractor will need to develop mathematical models, build a clinical pathway model, and integrate these models with the probability of apparent disease to provide a web-based tool. This will require significant expertise and resources. The budget could be influenced by factors such as the level of expertise required, the complexity of the models, and the resources needed to develop and integrate the models. A possible estimate for the budget could be in the range of $500,000 to $2,000,000.

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