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U.S. National Institutes of Health·United States of America

Infectious Diseases Clinical Trials Network (IDCTN) (UM1 Clinical Trial Required)

Closes 11/10/2026$5M – $15MGrants Notice
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Description

The National Institute of Allergy and Infectious Diseases (NIAID) is soliciting applications to create and operate the Infectious Diseases Clinical Trials Network (IDCTN). The network will consist of Clinical Trial Evaluation Units (CTEUs) that design and run clinical trials for emerging and chronic infectious diseases, and a Network Coordination Center (NCC) that provides administrative, operational, and scientific coordination. Awardees will receive a UM1 cooperative agreement (complex‑structure) and are expected to collaborate closely with NIH staff, contribute to protocol development, data management, regulatory compliance, and mentorship of early‑career investigators. Funding is anticipated at roughly $10 M (estimated) with a potential start date of March 2027. The effort is national in scope and open to a wide range of eligible entities (public, nonprofit, for‑profit, tribal, etc.) but excludes foreign organizations. • UM1 cooperative agreement for a national clinical‑trial network • Requires establishment of CTEUs and an NCC with NIH‑staff partnership • Focus on therapeutics, vaccines, biologics, diagnostics, and devices for infectious diseases • Eligible applicants: U.S. public, nonprofit, for‑profit, tribal, and educational institutions • Estimated total funding ≈ $10 M; award anticipated March 2027, project start March 2027 • Application deadline: 5 PM local time, November 10 2026 (open Oct 10 2026)

Attached files

Contact

Marina S. Lee, Ph.D.

[email protected]

(240) 627-3304

Key dates

Opened
11/18/2025
Closes
11/10/2026
Projected award
3/1/2027
Duration
4 years

Last updated

Details

Type
Grants Notice
Industry
Healthcare and Medical Services
NAICS
541714
Solicitation №
RFA-AI-27-002

Budget estimate

$5,000,000 – $15,000,000

The NOFO lists an estimated total funding of $10,000,000 for the IDCTN effort, while the forecasted version mentions $29,000,000. Assuming the award will be split among multiple CTEU/NCC partners, a single organization could realistically receive anywhere from $5 M to $15 M, depending on the scope of its unit and the level of coordination required. Factors influencing the budget include the size of the clinical trial portfolio the applicant proposes, the amount of infrastructure (e.g., trial sites, data‑management systems) they will provide, and any additional subcontracting or partnership arrangements.

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