Clinical Trials in Organ Transplantation in Children and Adults

The National Institute of Allergy and Infectious Diseases (NIAID) is seeking to support clinical trials in organ transplantation in children and adults through the Clinical Trials in Organ Transplantation in Children and Adults (CTOT-CA) program. The goal of the CTOT-CA is to improve the outcome of organ transplantation through clinical trials with mechanistic studies. The program will support multicenter clinical trials, with associated studies of immune mechanisms, in heart, lung, kidney, liver, and intestinal transplantation. • The program will also support clinical trials of non-hematopoietic cellular transplantation as replacement therapies; vascularized composite tissue transplantation; and transplantation of bone marrow or mesenchymal stem cells, or of immunologically active cells, as adjuncts to organ transplantation. • The NIAID will provide an estimated $11,280,000 in funding for this opportunity. • The opportunity is open to a variety of eligible applicants, including county governments, special district governments, for-profit organizations, non-profits, and institutions of higher education.