Description
The National Institute of Allergy and Infectious Diseases (NIAID) seeks to fund multidisciplinary U54 Centers for Structural Biology focused on HIV and other infectious diseases. Centers will determine high‑resolution 3‑D structures of viral and host biomolecules, develop computational and experimental tools, and provide shared core resources, training, and collaborative development awards to the broader research community. Funding is provided as a cooperative agreement (U54) with an estimated total award pool of $33 M and a ceiling of $3.5 M per center. Eligible applicants include U.S. public and private nonprofit institutions, for‑profit entities (excluding small businesses), and various government entities; foreign organizations are not eligible. The award period is expected to begin July 1 2027, with a submission deadline of May 28 2027.
• Supports high‑resolution structural biology, computational modeling, and structure‑guided drug design.
• Requires a Data Management & Sharing Plan and annual RPPR reporting.
• Provides shared core facilities, training, and collaborative development awards (1‑3 CDAs per year).
• Cooperative agreement implies substantial NIH programmatic involvement.
• Applicants must be U.S. entities; foreign sub‑awards are prohibited.
• Total anticipated funding $33 M; individual center award up to $3.5 M over multiple years.