Childhood Asthma in Urban Settings Clinical Research Network

The National Institute of Allergy and Infectious Diseases (NIAID) is seeking to advance its mission through the continued support of the Childhood Asthma in Urban Settings Clinical Research Network (CAUSE) network. The CAUSE network will support multi-site clinical studies and trials on the prevention and treatment of asthma in economically disadvantaged pediatric populations where disease burden is high. The objectives of the CAUSE network are to develop and test innovative hypotheses and strategies for asthma prevention, identify and test new treatment targets, and continue to explore the risk relationship between upper and lower airway. • The CAUSE network will support multi-site clinical studies and trials on the prevention and treatment of asthma in economically disadvantaged pediatric populations. • The network will use systems biology approaches to identify disease endotypes that may be suitable targets for existing and novel therapeutic modalities. • The estimated funding for this opportunity is $8,380,000.