Undiagnosed Diseases Network (UDN) Clinical and Data Coordinating Center

The National Institute of Neurological Disorders and Stroke (NINDS) is forecasting a new phase of the Undiagnosed Diseases Network (UDN) and intends to fund a Clinical and Data Coordinating Center (CDCC). The CDCC will serve as the operational hub for the network, handling participant recruitment, patient navigation, protocol and regulatory management, data sharing, analytics innovation, systematic re‑evaluation of unsolved cases, training, implementation‑science research, and performance monitoring. Applicants must demonstrate robust infrastructure, governance, regulatory capacity, informatics systems, and stakeholder partnerships to assume CDCC responsibilities with minimal start‑up time. This is a forecast only; no solicitation is active yet, but the posting gives potential applicants time to plan collaborations and prepare a responsive proposal. • Lead agency: NIH (NINDS) – Cooperative Agreement (CA) funding instrument. • Target: Organizations capable of national‑scale clinical coordination and data management for rare‑disease research. • Key responsibilities: participant support, data integration, regulatory oversight, analytics, training, and translation of diagnostic approaches into clinical practice. • Eligibility: Wide range of entities (for‑profit, nonprofit, tribal, state, local governments, etc.). • Estimated timeline: Posting Sep 2026 → anticipated application response May 2027 → award May 2027 → project start Apr 2028.