Biosurveillance and Biological Detection Capabilities Request for Information

The U.S. Department of Homeland Security is seeking information on biosurveillance and biological detection capabilities to support homeland security missions. The Department is interested in technologies, operational concepts, architectures, workflows, and integrated approaches capable of supporting domestic biosurveillance and biological awareness missions. The capabilities of interest include detection and identification of known or unknown biological threats, integrated biosurveillance and situational awareness, rapid methods to confirm detection of a biological incident, and biological incident risk analytics. Some key areas of interest include: • Detection of known biological threats • Detection of unknown or anomalous biological activity • Integrated biosurveillance and situational awareness • Rapid validation and characterization • Scalable and interoperable biosurveillance ecosystems The Department is particularly interested in capabilities that can operate in dynamic environments, provide near-laboratory-grade validation, and support operational decision-making.