Study for Dengue, Chikungunya, Zika, Hantaviruses, Crimean-Congo Haemorrhagic Fever (CCHF)

The United States Department of the Naval Medical Research Command (NMRC) intends to award a sole source contract to the University of Colombo to conduct a study on acute undifferentiated febrile illness (AUFI) surveillance for dengue, chikungunya, Zika, hantaviruses, and Crimean-Congo hemorrhagic fever in Sri Lanka. The study aims to recruit a cohort of patients, collect clinical and environmental exposure data, and perform testing for AUFI pathogens. The contractor will be required to perform various tasks, including recruiting patients, collecting samples, and conducting molecular diagnostics. • The contractor will recruit a cohort of 150-200 patients hospitalized for AUFI in Eastern Province Sri Lanka. • The contractor will collect detailed clinical, occupational, and environmental exposure data to identify associated risk factors for identified AUFI pathogens. • The contractor will carry out testing for AUFI pathogens utilizing species-specific molecular diagnostics. • The contractor will perform genotyping on dengue and determine the strain of chikungunya virus on positive specimens.