Intelligent Generator of Research (IGoR) - ISO

The Intelligent Generator of Research (IGoR) program aims to eliminate longstanding inefficiencies in research and accelerate the development of effective therapies for complex diseases by creating an AI-enabled interoperable research ecosystem. The program will develop four components: mechanistic disease models, an AI orchestration layer, a layered protocol architecture, and a distributed marketplace of validated laboratories. The program is a 5-year, 3-phase effort, and ARPA-H anticipates awarding to approximately three multidisciplinary teams. • The program will empower researchers to pursue bold, unconventional research directions that are currently too slow, too complex, or too resource-intensive. • The program will create a cycle of hypothesis generation, experimentation, and model refinement that enables researchers to create validated knowledge at least 10x more rapidly than conventional approaches. • The program will develop a distributed marketplace of validated laboratories that execute standardized protocols and return gold-standard data. • The program will be a collaborative effort between academia, non-profit organizations, and commercial entities.