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U.S. Department Of Health And Human Services·District of Columbia

Advanced Research Projects Agency for Health (ARPA-H) Small Business Innovation Research (SBIR)/Small Business Technology Transfer (STTR) Program

Closes 10/1/2026$600k – $3.5MRequest for Proposal
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Description

The ARPA‑H SBIR/STTR Broad Agency Announcement (BAA) seeks innovative, health‑focused research and development proposals from eligible U.S. small businesses. Eight topics are open, covering fertility diagnostics, bio‑adhesives, universal toxin‑removal platforms, non‑surgical endometriosis therapies, lineage commercialization, autoimmune disease diagnostics, and a virtual brain for neurosurgical robotics. Proposers submit a 4‑page Solution Summary (5 pages for Fast‑Track) by the Stage 1 deadline, then, if encouraged, a full Stage 2 proposal with technical presentations, cost breakdowns, and key‑personnel worksheets. Funding ceilings are roughly $600 k for Phase I and $3.5 M for Phase II per topic, with Phase I lasting up to 12 months and Phase II up to 36 months. The solicitation is set‑aside for SBA‑qualified small businesses and requires compliance with SBIR/STTR data‑rights, Section 508 accessibility, and human‑subjects/animal‑care regulations. • Eligible U.S. small businesses (≤500 employees) can submit up to nine SBIR/STTR proposals per fiscal year. • Eight research topics address high‑impact health challenges, each with defined technical objectives and anticipated budgets. • Phase I (≤12 mo, $600 k) proves feasibility; Phase II (24‑36 mo, $3.5 M) advances prototypes toward commercialization. • Fast‑Track combines Phase I and II in a single award; a separate commercial‑plan page is required.

Attached files

Contact

Business Innovation Division(Business Innovation Division)

[email protected]

Key dates

Opened
9/11/2026
Closes
10/1/2026
Duration
12 months

Last updated

Details

Type
Request for Proposal
Industry
Healthcare and Medical Services
NAICS
541715
Solicitation №
7599226SN106

Budget estimate

$600,000 – $3,500,000

The program caps Phase I awards at roughly $600,000 and Phase II at about $3,500,000 per topic. Depending on whether the proposer seeks only Phase I, Phase II, or a Fast‑Track award, the expected earnings range spans from six hundred thousand dollars up to three and a half million dollars.

AI estimate from the solicitation

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