Custom chemical synthesis

The National Institutes of Health (NIH) is seeking a vendor to provide 200 grams of (1S,2S)-trans-N-Boc-1,2-cyclopentanediamine, a chemical precursor used in the synthesis of cyclopentane peptide nucleic acids and incorporation into thyclotides. This acquisition is necessary to support ongoing preclinical research activities and advance the project to the next stage of development. The NIH is currently conducting a long-term research project funded by the NIH Office of AIDS Research focused on the development of this class of molecules for the detection, prevention, and treatment of HIV infection. • The required chemical is (1S,2S)-trans-N-Boc-1,2-cyclopentanediamine. • The quantity required is 200 grams. • The acquisition is necessary to support ongoing preclinical research activities. • The project is focused on the development of molecules for the detection, prevention, and treatment of HIV infection.