Description
The Protein ENGineering (PENG) program aims to establish a multifunctional, target-agnostic platform for precise, programmable editing of endogenous proteins. The program will explore multiple technical paths, progressively advancing their approaches from foundational validation to robust demonstrations of efficacy. The goal is to establish a foundational toolkit that allows researchers to directly and reversibly effect the functional layer of biology. Key aspects of the program include:
• Establishing a platform for protein engineering
• Exploring multiple technical paths for protein editing
• Focusing on foundational, bench-top laboratory models and complex in vitro tissue systems
• Encouraging teaming arrangements among potential proposers
• Anticipated release of Program Solicitation in July 2026