Chemical Screening and Optimization Facility (X01 Clinical Trial Not Allowed)

The National Institutes of Health (NIH) has announced a grant opportunity for the Chemical Screening and Optimization Facility. The goal of this facility is to advance non-hormonal contraceptive and reproductive health-related product development. The facility will provide preclinical services, including Investigational Device Exemption (IDE) or Investigational New Drug (IND)-enabling studies. • The facility will offer services such as protein generation, X-ray crystallography, high throughput screening, structure activity relationships, hit-to-lead generation, and drug metabolism. • The long-term objective is to enable a preclinical candidate for IND/IDE study(ies) that offers a safe therapeutic option in the field of contraception and/or reproductive health-related indications. • Eligible applicants include various organizations, such as Native American tribal organizations, non-profits, and small businesses. • The grant will support research and development of new products and technologies in the field of reproductive health.