This opportunity aims to support extramural research that investigates and mitigates challenges in clinical assay development due to preanalytical variability in biospecimens. The research will focus on understanding how different biospecimen preanalytical conditions affect emerging and clinically relevant biomarkers. The goal is to expedite biomarker clinical assay development through evidence-based standardization of biopsy handling practices. Key aspects of this opportunity include:
• Investigating preanalytical variability associated with biospecimen procurement and study
• Exploring how different biospecimen preanalytical conditions affect biomarkers
• Improving understanding of how analytical quantification of biomarkers is affected by biospecimen collection, processing, and storage procedures
• Supporting research that can lead to evidence-based standardization of biopsy handling practices
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Contact
National Institutes of Health(NIH Grants Information)
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