The National Cancer Institute (NCI) is seeking up to ten multidisciplinary Research Units (U01 cooperative agreements) to advance early detection of pancreatic ductal adenocarcinoma (PDAC) and its precursors. Awardees will develop and validate molecular and imaging biomarkers, create biorepositories of longitudinal biospecimens, and employ machine‑learning approaches to identify high‑risk populations. Units must collaborate across the consortium, share data and specimens, and contribute to steering‑committee activities. Funding is up to $600,000 per award, with no cost‑sharing required.
• Focus on PDAC early‑detection biomarkers (fluid‑based, imaging, genetic risk).
• Required collection of longitudinal biospecimens for a shared biorepository.
• Integration of computational/machine‑learning methods for biomarker discovery.
• Collaborative participation in consortium meetings, data sharing, and steering‑committee work.
• Cooperative agreement (U01) with up to $600K ceiling per award; total of 10 awards anticipated.
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