Supporting Community Application of Life-Saving Evidence to Prevent Injury and Violence (SCALE)

The CDC’s National Center for Injury Prevention and Control (NCIPC) is issuing a Funding Opportunity Notice (NOFO) to award up to 12 cooperative agreements that will strengthen community‑level injury, violence, overdose, and suicide prevention across the United States, including tribal populations. Funding (total $75 M) will support organizations that can implement evidence‑based strategies, disseminate messaging, and continuously improve programs to reduce morbidity and mortality from these public‑health threats. Applicants must have demonstrated expertise in injury‑related prevention, be able to work with state, local, territorial, or tribal health departments, and possess a public‑health‑oriented mission capable of rapid, evidence‑based response. • 12 awards; total estimated funding $75 M (≈ $6.25 M per award). • Cooperative Agreement (grant) mechanism; no cost‑sharing required. • Eligible entities: state, local, tribal governments; nonprofits (501 c 3 and others); for‑profit and small businesses; higher‑education institutions, etc. • Project start anticipated 09/01/2027; applications due 04/06/2027 (11:59 PM ET). • Activities include program implementation, community outreach, data‑driven evaluation, and scaling of proven injury‑prevention interventions. • Emphasis on reaching underserved and tribal communities and on rapid response to emerging public‑health threats.