Description
This NIH Funding Opportunity (PAR‑28‑093) invites applications for R34 planning grants to conduct pilot and feasibility studies that will lay the groundwork for larger efficacy, effectiveness, or services‑research trials targeting substance‑use prevention, treatment, recovery, and HIV‑related interventions. Eligible applicants include a broad range of public, nonprofit, tribal, and for‑profit entities (including foreign organizations) that can partner with end‑users such as policymakers, practitioners, and people with lived experience. Projects may focus on: • Development or adaptation of behavioral or biomedical interventions to prevent substance use or HIV transmission; • Evaluation of service delivery models, including comorbid pain, mental‑health, or medical conditions; • Implementation science studies to assess acceptability, feasibility, and scalability; • Creation of measurement tools, protocols, or data‑collection methods for future trials. No preliminary data required, but a clear theory of change or logic model is expected. The award ceiling is $450,000; the application window opens Jan 16 2027 and closes Jul 16 2029.