Economic and Modeling Analyses to Support Immunization Policy and Programs

The purpose of this notice of funding opportunity (NOFO) is to support research projects to develop data- and model-based evidence on the public health, epidemiological, and economic impacts of vaccines to support immunization policy and programs. The selected applicant will be expected to use modeling and economic analysis results to estimate and quantify critical indicators on the severity of vaccine preventable diseases and the benefits that can be achieved with vaccination. • The project will include developing mathematical, epidemiological, and/or decision tree models for any vaccine preventable disease of interest. • The project will also involve collecting the most recent data for the parameters of the model, including incidence, efficacy, possible side effects, and effectiveness of the vaccine. • The models will be expected to estimate the number of disease-associated outpatient visits, Emergency Department visits, hospitalizations, and deaths in the US each year. • The project will provide the following types of scientific evidence: the overall public health and economic burden of the vaccine preventable disease, the individual-level economic burden of the disease, and the public health and economic benefits of a robust immunization system.