The CDC, via the Department of the Interior’s Interior Business Center, seeks a single‑award, firm‑fixed‑price contract to develop a U.S.‑led biorisk management framework for poliovirus containment. The effort includes technical services, framework development, stakeholder engagement, workforce training, and delivery of implementation tools. The contractor will produce a complete biorisk management system, provide training to CDC staff, and create a Data Management Plan for public‑health data. The base period is one year with four optional twelve‑month extensions, and proposals must be submitted by September 16, 2026. Evaluation will consider technical acceptability and price reasonableness. • Scope: framework design, stakeholder coordination, training, implementation tools, data‑management planning. • Deliverables: detailed biorisk management framework, training curriculum, implementation toolkits, DMP, periodic progress reports. • Contract type: Firm‑Fixed‑Price, base year + 4 option years. • Required certifications: SAM registration, representations & certifications, small‑business subcontracting plan if applicable. • Mandatory submission items: technical volume (≤10 pages), pricing spreadsheet, DMP (if data collection involved).