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U.S. Department Of Health And Human Services·North Carolina

Support for Evaluating and Conducting Computational and Alternative Toxicological Methods for the National Institute of Environmental Health Sciences

Closes 12/19/2025$10M – $50MRequest for Proposal
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Description

The National Institute of Environmental Health Sciences (NIEHS) is seeking a contractor to provide support for evaluating and conducting computational and alternative toxicological methods. The contractor will be responsible for conducting and evaluating toxicological testing using computational and/or alternative approaches, also referred to as New Approach Methodologies (NAMs). The areas of focus for the research include population variability, susceptibility, developmental neurotoxicity, carcinogenicity, ecotoxicity, acute toxicity, and more. The contract will be a cost-plus fixed fee, term, level of effort contract with a base period of 12 months and nine successive 12-month term options for a total possible period of performance of 10 years. Some key points to consider: * The contractor must comply with established HHS EIT accessibility standards. * The contractor must provide a Technical Proposal, Business Proposal, and Excel Business Proposal Budget. * The Business Proposal must contain itemized cost and substantiating information to support the figures contained in the Excel spreadsheet budget fields. * The contractor must provide a list of personnel, their specific duties, and availability to the program. * The contractor must provide a detailed breakdown of costs, including labor hours, rates, and costs by category.

Attached files

Contact

Jason Williams(Contracting Officer)

[email protected]

(301) 443-3877

Key dates

Opened
11/3/2025
Closes
12/19/2025
Duration
10 years

Last updated

Details

Type
Request for Proposal
Industry
Healthcare and Medical Services
NAICS
541715
Solicitation №
75N96025R00004

Budget estimate

$10,000,000 – $50,000,000

The budget for this contract is not explicitly stated in the document. However, considering the contract type (cost-plus fixed fee) and the period of performance (10 years), the budget could be substantial. A rough estimate could be in the range of $10 million to $50 million, depending on the actual costs incurred and the fixed fee amount. This estimate is based on the assumption that the contractor will provide a team of researchers and support staff, and the costs will include labor, materials, equipment, and travel. The fixed fee amount will be added to the actual costs to determine the total budget.

AI estimate from the solicitation

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