Small R01s for Clinical Trials Targeting Diseases within the Mission of NIDDK (R01 Clinical Trial Required)

This Notice of Funding Announcement (NOFO) encourages the submission of pilot and feasibility clinical trials conducted in humans that will lay the foundation for larger clinical trials related to the prevention and/or treatment of diseases and conditions within the mission of NIDDK. The program will support small, short-term proof-of-concept clinical trials in humans to acquire preliminary data regarding the effects of the intervention, as well as feasibility data related to recruitment and retention, and study conduct. • The opportunity is open to various types of applicants, including for-profit organizations, non-profits, state governments, city or township governments, and public and state controlled institutions of higher education. • The award ceiling for this opportunity is $200,000. • The opportunity is related to the mission of NIDDK, which includes diseases such as diabetes, digestive, and kidney diseases. • The program aims to support clinical trials that will lead to more definitive, hypothesis-driven trials to improve understanding, diagnosis, prevention or treatment of the diseases studied and have the potential to impact clinical practice and/or public health.