Synthesis of Self-Amplifying Nucleic Acid Constructs

The United States Department of Agriculture (USDA) is seeking a service to generate five lipid nanoparticle encapsulated self-amplifying nucleic acid based on the genetic components of the alphavirus Venezuelan equine encephalitis virus (VEEV). This requirement is set aside for small business concerns. The contract will be a firm-fixed price requirements contract, and the award will be made to the offeror representing the best value to the Government, based on the lowest price technically acceptable criteria. The offeror must provide a detailed explanation of their company's capability, technical and management approach, and experience in providing similar services. The USDA requires delivery of all items 30 days after award, and the offeror must agree to hold their prices firm for 90 calendar days from the date specified for receipt of offers. • The service must generate five lipid nanoparticle encapsulated self-amplifying nucleic acid based on the genetic components of the alphavirus Venezuelan equine encephalitis virus (VEEV). • The contract will be a firm-fixed price requirements contract. • The award will be made based on the lowest price technically acceptable criteria. • The offeror must provide a detailed explanation of their company's capability, technical and management approach, and experience in providing similar services. • The USDA requires delivery of all items 30 days after award.