Limited Competition for the Continuation of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Clinical Centers (U01 Clinical Trial Required)

This limited‑competition Notice of Funding Opportunity (NOFO) invites the current COPE‑AKI clinical trial consortium sites to apply for a three‑year extension of the U01 cooperative‑agreement clinical centers and the associated scientific/data research center. The award will fund continued patient enrollment, long‑term follow‑up, data management, analysis, and dissemination of findings aimed at establishing a standard of care for survivors of stage 2‑3 acute kidney injury. Successful applicants will manage multi‑site clinical operations, coordinate with the NIDDK Data and Sample Biorepository, and comply with NIH data‑sharing and reporting requirements. • 3‑year U01 cooperative agreement for up to three Clinical Centers and one Scientific/Data Research Center • Estimated total funding ≈ $1.85 M (≈ $600 k per award) • Must be a current recipient of the original COPE‑AKI award (RFA‑DK‑20‑011) • Responsibilities include patient recruitment, protocol implementation, data collection, interim reporting, and final analysis • Requires a Data Management & Sharing Plan, annual RPPRs, and adherence to NIH grant policy