Single Source for the Continuation of the Caring for OutPatiEnts after Acute Kidney Injury (COPE-AKI) Scientific and Data Research Center (U01 Clinical Trial Required)

This Notice of Funding Opportunity (NOFO) invites a single‑source, three‑year renewal application from the existing Scientific and Data Research Center (SDRC) that supports the COPE‑AKI clinical trial consortium. The award is a Cooperative Agreement (U01) to complete enrollment, follow‑up, data analysis, and dissemination for a multicenter randomized trial focused on post‑hospitalization outcomes for acute kidney injury survivors. The SDRC will manage data coordination, central repository submissions, and overall trial governance, working closely with three clinical centers and NIH program staff. Funding is estimated at $1.8 million for the three‑year period. • Single‑source (sole source) competition – only the current SDRC holder may apply. • U01 Cooperative Agreement – NIH provides substantial scientific and technical oversight. • Scope: complete enrollment targets, participant follow‑up, data management, analysis, and results dissemination. • Duration: 3 years, with an anticipated start July 2027. • Estimated total funding: $1.8 M (≈ $600 K per year). • Eligibility limited to the existing SDRC; other organizations are ineligible. • Key contacts: Ivonne Schulman (agency contact) and NIDDK scientific/administrative contacts.