HEAL Initiative: Integrative Management of Chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers (RM1 Clinical Trial Required)

The NIH HEAL Initiative seeks to fund research centers that will implement and evaluate integrated clinical‑trial‑based interventions for patients with co‑occurring chronic pain (CP) and opioid use disorder (OUD). Awardees will lead a Coordination Center and multiple research projects (RM1 activity code) focused on health‑system level strategies, peer‑specialist involvement, implementation science, and scalability of proven patient‑level interventions. The effort is collaborative across NIDA, NIAAA, NIAMS, NIMH, NCCIH, and NINDS and requires adherence to NIH data‑sharing, human‑subjects, and reporting policies. Applications are due 1/26/2027; award expected 4/1/2027; project start 4/1/2027. Eligible entities include a broad range of public, nonprofit, tribal, and for‑profit organizations. • Focus: Integrated CP + OUD care at the health‑system level. • Funding mechanism: RM1 Clinical‑Trial‑Required research center grant (grant). • Deliverables: Coordination Center, multiple clinical‑trial projects, data sharing, annual RPPRs, final close‑out reporting. • Eligibility: State, local, tribal, nonprofit, higher‑education, small business, and other U.S. entities. • Key contacts: Shelley Su, Ph.D. (NIDA) – [email protected].