Cancer Intervention and Surveillance Modeling Network (CISNET) (U01 Clinical Trial Not Allowed)

The National Institutes of Health (NIH) is seeking applications for the Cancer Intervention and Surveillance Modeling Network (CISNET) to expand and extend the work of CISNET in specific priority areas where modeling can help optimize the translation of cancer research into practice. The purpose of this Notice of Funding Opportunity (NOFO) is to request applications for collaborative research projects using simulation and other modeling techniques for specific cancer types. The proposed research is expected to generate sophisticated, evidence-based tools capable of informing decisions on the most efficient utilization of existing and emerging technologies and strategies for the control of cancer. • The CISNET consortium uses simulation modeling to extend evidence provided by trial, epidemiologic, and surveillance data to guide public health research and priorities across the cancer continuum. • Applications should advance the practice of simulation modeling with the overarching goal of informing pressing decisions about cancer prevention and control. • The CISNET approach to modeling includes flexible broad-based disease models, multiple birth-cohort modeling, and comparative modeling. • The NOFO encourages projects aligned with NCI priorities that translate cancer research into practice across the cancer control continuum.