Toward Translation of Nanotechnology Cancer Interventions (TTNCI; R01 Clinical Trial Not Allowed)

The National Cancer Institute (NCI) encourages applications for advanced pre-clinical research, supporting translation of nanotechnology-based cancer diagnostics and therapeutics. The goal of this initiative is to mature experimental nanomedicines relying on nanoparticles and nano-devices that demonstrate strong potential to improve cancer treatment effectiveness. This will enable further development of proposed nanotechnology-based interventions to the stage in which they could continue on a developmental path towards the NCI Experimental Therapeutics (NExT) and other NCI translational programs. * The initiative focuses on advanced pre-clinical research for nanotechnology-based cancer diagnostics and therapeutics. * The goal is to mature experimental nanomedicines that demonstrate strong potential to improve cancer treatment effectiveness. * The proposed nanotechnology-based interventions should have the potential to continue on a developmental path towards the NCI Experimental Therapeutics (NExT) and other NCI translational programs. * Eligible applicants include various organizations such as non-profits, for-profit organizations, small businesses, and institutions of higher education.