Novel Surface Enhanced Raman Spectroscopy (SERS) Scanning Technology for Biodetection

The Department of Homeland Security (DHS) is seeking information on the utility of surface-enhanced Raman spectrometry in biodetection. The goal is to develop a SERS nanostructure prototype to detect bioagents of interest to DHS components and their stakeholders. The project may involve a period of performance of up to 36 months. Key components of the project include the development of a SERS nanostructure prototype, a Raman platform, and an adaptive signature library. * The SERS nanostructure prototype must adhere to cell surface proteins of a select agent. * The SERS nanostructure must be designed to give the optimal spectral signal for select agents. * The Raman platform must work efficiently with the SERS nanostructure prototype. * The adaptive library must be cloud-based and have the capability to update monthly.