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U.S. Department Of Defense·Virginia

Biological Technologies

Closes 9/30/2026$500k – $2MRequest for Proposal
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Description

The Defense Advanced Research Projects Agency (DARPA) Biological Technologies Office (BTO) is soliciting proposals that leverage biological properties and processes to revolutionize the ability to protect the nation’s warfighters. The proposals should focus on developing innovative solutions that can address various challenges, including biological and chemical threats, medical countermeasures, and novel approaches to tactical care and warfighter performance and recovery. Some of the topic areas of interest include: • Biological and/or chemical technology topic areas that fit the national security scope of BTO’s mission • Research into market opportunities, constraints, and communities affecting financing and commercialization of bioindustrial and biomedical technologies • Machine Learning (ML) and Artificial Intelligence (AI) approaches for biological data generation and assessment • Combat Casualty Care, including developing novel diagnostic, prophylactic, and therapeutic approaches for warfighter injury • Human Performance, including understanding and improving treatment of and resilience in neurological health, fatigue, cognition, and optimized human performance and teaming • Materials, Sensors, Processing, including designing novel materials, sensors, or processes that mimic or are inspired by biological systems • Agricultural and Environmental, including understanding and addressing emerging threats to global food, water, and ecosystem stability • Security, Safety, and Surveillance, including developing new technologies and approaches to ensure the biosafety and biosecurity of biological hardware and data • Biomedical and Biodefense, including developing new technologies for rapid, automated, and resilient manufacturing, delivery, and distribution of critical molecules for applications in therapeutics, chemical and biological defense. Proposers should submit an abstract and, if invited, a full proposal that outlines their approach, technical team, and cost and schedule realism.

Attached files

Contact

[email protected]

Key dates

Opened
10/1/2025
Closes
9/30/2026

Last updated

Details

Type
Request for Proposal
Industry
Aerospace and Defense
NAICS
541714
Solicitation №
HR001126S0003

Budget estimate

$500,000 – $2,000,000

The budget for this opportunity could range from $500,000 to $2,000,000, considering the complexity and scope of the project. The cost and schedule realism will be evaluated, and the proposer's prior experience and technical approach will also be taken into account. The funding opportunity allows for multiple award instrument types, including Procurement Contracts, Cooperative Agreements, and Other Transaction Agreements.

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