Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed)

The purpose of this Notice of Opportunity Announcement (NOFO) is to invite applications proposing the innovative analysis of existing social science, behavioral, administrative, and neuroimaging data to study the etiology and epidemiology of drug using behaviors and related disorders, prevention of drug use and HIV, and health service utilization. This FOA encourages the analyses of public use and other extant community-based or clinical datasets to their full potential in order to increase our knowledge of etiology, trajectories of drug using behaviors and their consequences including morbidity and mortality, risk and resilience in the development of psychopathology, strategies to guide the development, testing, implementation, and delivery of high quality, effective and efficient services for the prevention and treatment of drug abuse and HIV. • The opportunity is open to various types of organizations, including nonprofits, institutions of higher education, and small businesses. • The application due date is December 3, 2027. • The award is expected to be made on April 1, 2026. • The estimated funding for this opportunity is $2,000,000. • The opportunity aims to promote research on substance use disorders and related topics.