Research Resource for a National Swine Resource and Research Center (U42 Clinical Trial Not Allowed)

The National Institutes of Health is seeking applications to provide continuing support for a National Swine Resource and Research Center (NSRRC). The NSRRC aims to enable gold-standard science in biomedical research by serving as a centralized national resource for the creation, breeding, cryopreservation, and distribution of genetically modified models. The center will provide genotyping and phenotyping services, infectious disease monitoring, and protocol distribution to facilitate their use for biomedical research. The center will also serve as a source of information and training related to the care and use of these models in biomedical research. • The NSRRC will consolidate essential functions to reduce variability and improve reproducibility across studies. • The center will eliminate redundancy and high costs associated with individual laboratories maintaining separate facilities and breeding programs for these models. • The center will provide access to consistent, high-quality, specific pathogen-free models for biomedical research. • The center will serve as a resource to lead the development of alternative or complementary approaches available, including new approach methodologies (NAMs), alongside in vivo models.