FDA - Intent to Sole Source Molecular Operating Environment

The U.S. Food and Drug Administration intends to award a sole source contract to Chemical Computing Group ULC to enhance the Division of Applied Regulatory Science (DARS) analytical capabilities. The contract will provide the Molecular Operating Environment (MOE), a comprehensive cheminformatics and molecular modeling software platform. The anticipated period of performance will consist of a base year, plus four one-year option periods. The contract will enable three-dimensional (3D) structural analysis and representation, which has proven essential for conducting more robust evaluations of adverse drug reactions. Key aspects of the job include: • Providing the molecular modeling software package to communicate and provide customizable molecular docking models • Updating chemical descriptors and supporting chemical database management • Providing modeling diverse types of molecules and molecular interactions (organic, metallic, biomolecules)