Description
The FDA is seeking a fully automated laboratory vitrification system designed for preparing cryo-EM specimens by rapidly freezing biological samples in their native, hydrated state. The system should be a stand-alone, fully-automated vitrification system with features such as automated vitrification capability, environmental control, sample handling, blotting system, cryogen system, user interface, and safety features. The system should also seamlessly integrate with an existing Tundra Cryo-Transmission Electron Microscope (Cryo-TEM).
Key features and requirements include:
* Fully automated vitrification system
* Environmental control with temperature and humidity monitoring
* Sample handling compatible with standard 3mm cryo-EM grids
* Blotting system with dual-sided blotting capability and adjustable blot force and time
* Cryogen system with liquid ethane capability and temperature monitoring and control
* User interface with touchscreen and programmable protocols
* Safety features including enclosed working chamber, gas detection, and emergency stop functionality
* Integration with existing Tundra Cryo-Transmission Electron Microscope (Cryo-TEM)
* Minimum one-year full manufacturer's warranty