The Department of Veterans Affairs, Network Contracting Office 6, intends to award a sole source purchase order to Duke University Substrate Services Core & Research Support for a Research and Development study. The study involves metabolomics and proteomic lab services to inform plasma-based signature of outcomes after HCV cure and are relevant to Veterans with severe liver disease analyses. The contractor will prepare liver tissue and conduct targeted mass spectrometry to profile metabolites and proteins in tissue. The goal is to develop novel risk stratification tools with high impact on clinical care of Veterans with severe liver disease.
Some key aspects of the job include:
• Preparing liver tissue for analysis
• Conducting targeted mass spectrometry to profile metabolites and proteins
• Using metabolomic discovery to develop novel risk stratification tools
• Informing plasma-based signature of outcomes after HCV cure
• Analyzing relevant data for Veterans with severe liver disease
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