The Department of Veterans Affairs, Iowa City VA Healthcare System Research Department is seeking information on 3D bioprinters for a research project. The project involves 3D bioprinted human corneal endothelial grafts for endothelial keratoplasty transplantations. The bioprinter should have specific features such as the ability to combine extrusion printing for high-viscosity biomaterials with droplet-based nanoliter deposition, and enable drop-by-drop spraying of low-viscosity biomaterials. The bioprinter should also have a camera-guided printing system and allow for precise spatial targeting.
Some key features of the bioprinter include:
• Ability to combine extrusion printing for high-viscosity biomaterials with droplet-based nanoliter deposition
• Enables drop-by-drop spraying of low-viscosity biomaterials such as collagen
• Performs 5-way multi-crosslinking capabilities
• Circulates biomaterial suspensions within the syringe to prevent density gradients
• Includes a high-resolution camera directly on the printhead block for real-time printing path adjustments
• Enables contact lens specific printing capability
• Allows for integration with external objects or devices
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